发明申请
- 专利标题: MULTIMERIC MULTIEPITOPE INFLUENZA VACCINES
- 专利标题(中): 多种多药流感疫苗
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申请号: US14263359申请日: 2014-04-28
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公开(公告)号: US20140286982A1公开(公告)日: 2014-09-25
- 发明人: Tamar BEN-YEDIDIA , Yossi SINGER
- 申请人: BIONDVAX PHARMACEUTICALS LTD.
- 申请人地址: IL Ness Ziona
- 专利权人: BIONDVAX PHARMACEUTICALS LTD.
- 当前专利权人: BIONDVAX PHARMACEUTICALS LTD.
- 当前专利权人地址: IL Ness Ziona
- 主分类号: C07K14/005
- IPC分类号: C07K14/005
摘要:
An isolated polynucleotide encoding an influenza multi-epitope polypeptide, wherein the multi-epitope polypeptide comprises multiple copies of a plurality of influenza virus peptide epitopes wherein the polypeptide is B(X1ZX2Z . . . Xm)nB or B(X1)nZ(X2)nZ . . . (Xm)nB; wherein B is an optional sequence of 1-4 amino acid residues; n is at each occurrence independently an integer of 2-50; m is an integer of 3-15; each of X1, X2 . . . Xm is an influenza peptide epitope of 4-24 amino acid residues; and Z at each occurrence is a bond or a spacer of 1-4 amino acid residues.
公开/授权文献
- US09353159B2 Multimeric multiepitope influenza vaccines 公开/授权日:2016-05-31
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