发明申请
- 专利标题： BLADDER CANCER TREATMENT AND METHODS
- 专利标题（中）： 乳腺癌治疗和方法
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申请号： US14173734申请日： 2014-02-05
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公开(公告)号： US20140288143A1公开(公告)日： 2014-09-25
- 发明人: Bastiaan Nuijen , Ernie Pfadenhauer , Jos H. Beijnen , Luigi Lenaz , Shanta Chawla , Mario Beer
- 申请人： Spectrum Pharmaceuticals, Inc.
- 申请人地址： US CA Irvine
- 专利权人： Spectrum Pharmaceuticals, Inc.
- 当前专利权人： Spectrum Pharmaceuticals, Inc.
- 当前专利权人地址： US CA Irvine
- 主分类号： A61K31/404
- IPC分类号： A61K31/404 ; A61K47/18 ; A61K47/26 ; A61K47/10 ; A61K47/02
摘要：
Therapeutic compositions comprising an indoloquinone compound and various bladder cancer treatments and methods are disclosed. More specifically, bladder cancer treatments include the intravesical administration of apaziquone immediately following transurethral resection. Also disclosed are therapeutic compositions comprising an indoloquinone compound and a formulation vehicle. The formulation vehicle improves the solubility and stability of the indoloquinone compound. Additionally, the coating compositions can include coating agents that provide better adhesion of the coating composition to the bladder wall during intravesical delivery of the coating composition.
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