发明申请
- 专利标题： ANTIBODY FOR DETECTING EPITHELIAL OVARIAN CANCER MARKER AND METHOD FOR DIAGNOSING EPITHELIAL OVARIAN CANCER
- 专利标题（中）： 用于检测上皮癌标记物的抗体及诊断上皮癌的方法
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申请号： US14234783申请日： 2012-07-26
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公开(公告)号： US20140295455A1公开(公告)日： 2014-10-02
- 发明人: Maki Sogabe , Tomomi Kubota , Akira Togayachi , Yuzuru Ikehara , Hisashi Narimatsu , Hiromichi Sawaki , Hayao Nakanishi , Toru Nakanishi
- 申请人： Maki Sogabe , Tomomi Kubota , Akira Togayachi , Yuzuru Ikehara , Hisashi Narimatsu , Hiromichi Sawaki , Hayao Nakanishi , Toru Nakanishi
- 申请人地址： JP Tokyo
- 专利权人： National Institute of Advanced Industrial Science and Technology
- 当前专利权人： National Institute of Advanced Industrial Science and Technology
- 当前专利权人地址： JP Tokyo
- 优先权： JP2011-163299 20110726
- 国际申请： PCT/JP2012/068980 WO 20120726
- 主分类号： G01N33/574
- IPC分类号： G01N33/574 ; C07K16/40
摘要：
The present invention provides an antibody capable of specifically recognizing and detecting the highly specific cancer marker with respect to the epithelial ovarian cancer, or a fragment of the antibody. The present invention provides an anti-β1,3-N-acetylglucosaminyltransferase 3 antibody for diagnosis of epithelial ovarian cancer, i.e., an antibody for detection of a glycosyltransferase β1,3-N-acetylglucosaminyltransferase 3 as an epithelial ovarian cancer marker. The antibody recognizes, as an epitope, a part of a polypeptide of the enzyme consisting of the amino acid sequence represented by SEQ ID NO: 1.
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