发明申请
US20140371266A1 Mono Quaternary Ammonium Salts and Methods for Modulating Neuronal Nicotinic Acetylcholine Receptors
审中-公开
单体季铵盐和调节神经元烟碱乙酰胆碱受体的方法
- 专利标题： Mono Quaternary Ammonium Salts and Methods for Modulating Neuronal Nicotinic Acetylcholine Receptors
- 专利标题（中）： 单体季铵盐和调节神经元烟碱乙酰胆碱受体的方法
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申请号： US14470715申请日： 2014-08-27
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公开(公告)号： US20140371266A1公开(公告)日： 2014-12-18
- 发明人: Peter CROOKS , Linda P. DWOSKIN , Guangrong ZHENG , Sangeetha SUMITHRAN , Zhenfa ZHENG
- 申请人： University of Kentucky Research Foundation
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; C07D215/10 ; C07D217/10 ; C07D401/06 ; C07D213/20 ; C07D213/30
摘要：
Provided are monoquaternary ammonium compounds which are modulators of nicotinic acetylcholine receptors. Also provided are methods of using the compounds for modulating the function of a nicotinic acetylcholine receptor, and for the prevention and/or treatment of central nervous system disorders, substance use and/or abuse, and gastrointestinal tract disorders.
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