发明申请
US20150018349A1 SUBSTITUTED N-(3-(PYRIMIDIN-4-YL)PHENYL)ACRYLAMIDE ANALOGS AS TYROSINE RECEPTOR KINASE BTK INHIBITORS
有权
取代的N-（3-（吡咯烷-4-基）苯基）丙烯酰胺类似物作为酪氨酸受体激酶激酶抑制剂
- 专利标题： SUBSTITUTED N-(3-(PYRIMIDIN-4-YL)PHENYL)ACRYLAMIDE ANALOGS AS TYROSINE RECEPTOR KINASE BTK INHIBITORS
- 专利标题（中）： 取代的N-（3-（吡咯烷-4-基）苯基）丙烯酰胺类似物作为酪氨酸受体激酶激酶抑制剂
-
申请号： US14228184申请日： 2014-03-27
-
公开(公告)号： US20150018349A1公开(公告)日： 2015-01-15
- 发明人: David J. Bearss , Hariprasad Vankayalapati , Venkataswamy Sorna , Steven L. Warner , Sunil Sharma
- 申请人： University of Utah Research Foundation
- 申请人地址： US UT Salt Lake City
- 专利权人： University of Utah Research Foundation
- 当前专利权人： University of Utah Research Foundation
- 当前专利权人地址： US UT Salt Lake City
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D239/48 ; C07D239/30 ; C07D239/42
摘要：
In one aspect, the invention relates to substituted N-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of the BTK kinase; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the BTK kinase. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
公开/授权文献
信息查询
