Invention Application
- Patent Title: ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9)
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Application No.: US14487932Application Date: 2014-09-16
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Publication No.: US20150031870A1Publication Date: 2015-01-29
- Inventor: SIMON MARK JACKSON , Nigel Pelham Clinton Walker , Derek Evan Piper , Wenyan Shen , Chadwick Terence King , Randal Robert Ketchem , Christopher Mehlin , Teresa Arazas Carabeo
- Applicant: Amgen Inc.
- Main IPC: C07K16/40
- IPC: C07K16/40
Abstract:
Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described.
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