发明申请
- 专利标题： MICROORGANISMS FOR THE PRODUCTION OF 5-HYDROXYTRYPTOPHAN
- 专利标题（中）： 用于生产5-羟基吡啶的微生物
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申请号： US14382152申请日： 2013-02-28
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公开(公告)号： US20150037849A1公开(公告)日： 2015-02-05
- 发明人: Eric Michael Knight , Jiangfeng Zhu , Jochen Förster , Hao Luo
- 申请人： DANMARKS TEKNISKE UNIVERSITET
- 优先权： EP12157540.1 20120229
- 国际申请： PCT/EP2013/054018 WO 20130228
- 主分类号： C12P13/22
- IPC分类号： C12P13/22 ; C12N15/81 ; C12N9/06 ; C12N9/78 ; C12N9/88 ; C12N9/04 ; C12N15/70 ; C12N9/02
摘要：
Recombinant microbial cells and methods for producing 5-hydroxytryptophan (5HTP) using such cells are described. More specifically, the recombinant microbial cell comprises an exogenous gene encoding an L-tryptophan hydroxylase, and means for providing tetrahydrobiopterin (THB). Related sequences and vectors for use in preparing such recombinant microbial cells are also described.
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