Invention Application
- Patent Title: PROTEIN PURIFICATION METHODS TO REDUCE ACIDIC SPECIES
- Patent Title (中): 蛋白质纯化方法减少酸性物种
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Application No.: US14584492Application Date: 2014-12-29
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Publication No.: US20150141623A1Publication Date: 2015-05-21
- Inventor: Natarajan RAMASUBRAMANYAN , Lihua YANG , Matthew Omon HERIGSTAD , Hong YANG , Christopher CHUMSAE
- Applicant: AbbVie, Inc.
- Main IPC: C07K16/24
- IPC: C07K16/24 ; C07K1/22 ; C07K1/20 ; C07K1/18
Abstract:
The instant invention relates to the field of protein production and purification, and in particular to compositions and processes for controlling the amount of charge variants, aggregates, and fragments of a protein of interest, as well as host cell proteins, present in purified preparations by applying particular chromatography conditions during such protein purification.
Public/Granted literature
- US09346879B2 Protein purification methods to reduce acidic species Public/Granted day:2016-05-24
Information query
