Invention Application
US20150202316A1 LUNG CANCER SPECIFIC PEPTIDES FOR TARGETED DRUG DELIVERY AND MOLECULAR IMAGING 有权
靶向药物递送和分子成像的肺癌特异性肽

  • Patent Title: LUNG CANCER SPECIFIC PEPTIDES FOR TARGETED DRUG DELIVERY AND MOLECULAR IMAGING
  • Patent Title (中): 靶向药物递送和分子成像的肺癌特异性肽
  • Application No.: US14599291
    Application Date: 2015-01-16
  • Publication No.: US20150202316A1
    Publication Date: 2015-07-23
  • Inventor: Han-Chung WUYi-Hsuan CHI
  • Applicant: Academia Sinica
  • Main IPC: A61K47/48
  • IPC: A61K47/48 G01N33/574 A61K31/704
LUNG CANCER SPECIFIC PEPTIDES FOR TARGETED DRUG DELIVERY AND MOLECULAR IMAGING
Abstract:
A conjugate is disclosed. The conjugate comprises (a) an isolated or a synthetic targeting peptide of less than 15 amino acid residues in length, comprising an amino acid sequence having at least 90% identity to a sequence selected from the group consisting of SEQ ID NOs: 1-8; and (b) a component conjugated to the targeting peptide, the component being selected from the group consisting of a drug delivery vehicle, an anti-cancer drug, a micelle, a nanoparticle, a liposome, a polymer, a lipid, an oligonucleotide, a peptide, a polypeptide, a protein, a cell, an imaging agent, and a labeling agent. Methods of treating lung cancer and detecting lung cancer cells are also disclosed.
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