发明申请
US20150218172A1 Pyrrolo[2,3-D]Pyrimidine Tropomyosin-Related Kinase Inhibitors
审中-公开
吡咯并[2,3-D]嘧啶原肌球蛋白相关激酶抑制剂
![Pyrrolo[2,3-D]Pyrimidine Tropomyosin-Related Kinase Inhibitors](/docs/US/2015-08-06/US20150218172A1/abs.jpg.600x600.jpg)
- 专利标题： Pyrrolo[2,3-D]Pyrimidine Tropomyosin-Related Kinase Inhibitors
- 专利标题（中）： 吡咯并[2,3-D]嘧啶原肌球蛋白相关激酶抑制剂
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申请号： US14428997申请日： 2013-09-26
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公开(公告)号： US20150218172A1公开(公告)日： 2015-08-06
- 发明人: Mark David Andrews , Sharanjeet Kaur Bagal , David Graham Brown , Karl Richard Gibson , Kiyoyuki Omoto , Thomas Ryckmans , Yogesh Sabnis , Sarah Elizabeth Skerratt , Paul Anthony Stupple
- 申请人： PFIZER LIMITED
- 申请人地址： GB Sandwich, Kent, UK
- 专利权人： Pfizer Limited
- 当前专利权人： Pfizer Limited
- 当前专利权人地址： GB Sandwich, Kent, UK
- 国际申请： PCT/IB2013/058890 WO 20130926
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/519
![Pyrrolo[2,3-D]Pyrimidine Tropomyosin-Related Kinase Inhibitors](/abs-image/US/2015/08/06/US20150218172A1/abs.jpg.150x150.jpg)
摘要：
The present invention relates to compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine, in particular as Trk antagonists.
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