Invention Application
US20150238439A1 COMPOSITIONS AND METHODS FOR MODULATING DNMT1 INHIBITOR ACTIVITY
有权
用于调节DNMT1抑制剂活性的组合物和方法
- Patent Title: COMPOSITIONS AND METHODS FOR MODULATING DNMT1 INHIBITOR ACTIVITY
- Patent Title (中): 用于调节DNMT1抑制剂活性的组合物和方法
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Application No.: US14426399Application Date: 2013-09-06
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Publication No.: US20150238439A1Publication Date: 2015-08-27
- Inventor: Francesca R. Salipur , Paula J. Bates , Elsa Merit Reyes-Reyes , Bo Xu , Gerald B. Hammond
- Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
- International Application: PCT/US13/58566 WO 20130906
- Main IPC: A61K31/045
- IPC: A61K31/045 ; A61K38/06 ; A61K31/22 ; A61K31/198
Abstract:
Some aspects of the invention include attenuating DNMT1 inhibitor activity in an animal comprising administering an antioxidant. Other aspects of the invention include methods comprising administering a composition comprising a DNMT1 inhibitor and an antioxidant. In some instances in the methods, the animal is undergoing a treatment for cancer. Additional aspects of the invention include compositions comprising a DNMT1 inhibitor and an antioxidant.
Public/Granted literature
- US09737493B2 Compositions and methods for modulating DNMT1 inhibitor activity Public/Granted day:2017-08-22
Information query
