发明申请
US20150274664A1 SUBSTITUTED CYCLOPROPYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT
审中-公开
取代的环丙基化合物，包含这些化合物的组合物和处理方法
- 专利标题： SUBSTITUTED CYCLOPROPYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT
- 专利标题（中）： 取代的环丙基化合物，包含这些化合物的组合物和处理方法
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申请号： US14431366申请日： 2013-09-25
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公开(公告)号： US20150274664A1公开(公告)日： 2015-10-01
- 发明人: John J. Acton , Scott D. Edmondson , Ping Liu , Michael W. Miller , Harold B. Wood , Byron G. DuBois , William B. Geiss
- 申请人： John J. ACTON , Scott D. EDMONDSON , Ping LIU , Michael W. MILLER , Harold B. WOOD , Byron G. DUBOIS , William B. GEISS , MERCK SHARP & DOHME CORP.
- 申请人地址： US NJ Rahway
- 专利权人： Marck Sharp & Dohme Corp.
- 当前专利权人： Marck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 国际申请： PCT/US13/61567 WO 20130925
- 主分类号： C07D211/60
- IPC分类号： C07D211/60 ; C07D401/12 ; C07D413/04 ; C07D401/14 ; C07D401/04
摘要：
Substituted cyclopropyl piperidinyl compounds and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR-119. Pharmaceutical compositions and methods of treatment are also included.
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