Invention Application
- Patent Title: TARGETING OF EWS-FLI1 AS ANTI-TUMOR THERAPY
- Patent Title (中): EWS-FLI1作为抗肿瘤治疗的目标
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Application No.: US14696005Application Date: 2015-04-24
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Publication No.: US20150329488A1Publication Date: 2015-11-19
- Inventor: Jeffrey A. Toretsky , Aykut Uren , Milton Lang Brown , Yali Kong
- Applicant: Georgetown University
- Main IPC: C07D209/38
- IPC: C07D209/38 ; A61K45/06 ; A61K31/404
Abstract:
Peptides and compounds are provided that function as EWS-FLI1 protein inhibitors. The peptides and compounds have utility in the treatment of Ewing's sarcoma family of tumors. Also provided are methods of preparing the compounds and assays for identifying inhibitors of EWS-FLI1 protein.
Public/Granted literature
- US09758481B2 Targeting of EWS-FLI1 as anti-tumor therapy Public/Granted day:2017-09-12
Information query
