发明申请
- 专利标题： NEW SYNTHESIS PROCESS OF ANTIPARASITIC DRUG SELAMECTIN
- 专利标题（中）： 抗生素药物的新合成方法
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申请号： US14389802申请日： 2013-04-02
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公开(公告)号： US20150329581A1公开(公告)日： 2015-11-19
- 发明人: Mingxing Yin , Jianchao Wu , Jian Chai
- 申请人： Zhejiang Hisun Pharmaceutical Co., Ltd.
- 申请人地址： CN Taizhou
- 专利权人： Zhejiang Hisun Pharmaceutical Co., Ltd.
- 当前专利权人： Zhejiang Hisun Pharmaceutical Co., Ltd.
- 当前专利权人地址： CN Taizhou
- 优先权： CN201210102405.7 20120403
- 国际申请： PCT/CN2013/073604 WO 20130402
- 主分类号： C07H17/08
- IPC分类号： C07H17/08
摘要：
Provided in the present invention are novel key intermediates of selamectin and the preparation method thereof. Also provided is a new synthesis process, using doramectin as a starting material, and obtaining selamectin via hydrogenation, oxidation, oximation and desugaring. The new process of the present invention has few steps, and is simple to operate, high in yield, low in cost and causes little pollution, and is more suitable for large scale industrial production.
公开/授权文献
- US10053483B2 Synthesis process of antiparasitic drug selamectin 公开/授权日：2018-08-21