发明申请
- 专利标题： POLYNUCLEOTIDE ENRICHMENT USING CRISPR-CAS SYSTEMS
- 专利标题（中）： 使用CRISPR-CAS系统的多核苷酸增殖
-
申请号： US14804068申请日： 2015-07-20
-
公开(公告)号： US20160017396A1公开(公告)日： 2016-01-21
- 发明人: Gordon M. Cann , Jeffrey G. Mandell , Alex Aravanis , Steven Norberg , Dmitry K. Pokholok , Frank J. Steemers , Farnaz Absalan , Leila Bazargan
- 申请人： ILLUMINA, INC.
- 申请人地址： US CA San Diego
- 专利权人： ILLUMINA, INC.
- 当前专利权人： ILLUMINA, INC.
- 当前专利权人地址： US CA San Diego
- 主分类号： C12P19/34
- IPC分类号： C12P19/34
摘要：
A method for enriching a target nucleic acid comprising providing an endonuclease system having a crRNA or a derivative thereof, and a Cas protein or a variant thereof. The crRNA or the derivative thereof contains a target-specific nucleotide region substantially complementary to a region of the target nucleic acid; contacting the target nucleic acid with the endonuclease system to form a complex; and separating the complex and thereby enriching for the target nucleic acid.
公开/授权文献
- US10457969B2 Polynucleotide enrichment using CRISPR-Cas systems 公开/授权日：2019-10-29
信息查询
