Invention Application
- Patent Title: TETRACYCLIC BROMODOMAIN INHIBITORS
- Patent Title (中): 四氯化硼抑制剂
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Application No.: US14774866Application Date: 2014-03-12
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Publication No.: US20160039821A1Publication Date: 2016-02-11
- Inventor: Steven D. Fidanze , Dachun Liu , Robert A. Mantei , Keith F. McDaniel , John Pratt , George S. Sheppard , Le Wang , Andrew Bogdan , James H. Holms , Justin D. Dietrich , Jasmina Marjanovic , Lisa A. Hasvold , Yujia Dai
- Applicant: ABBVIE INC.
- International Application: PCT/CN2014/000258 WO 20140312
- Main IPC: C07D471/22
- IPC: C07D471/22 ; C07D471/16

Abstract:
The present invention provides for compounds of formula (I) wherein R1, R2, R6, Y1, Y2, Y3, A1, A2, A3 and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
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