A method for configuring a high-speed serial bus parameter, including sending an application signal from a transmit end of a high-speed serial bus to a receive end of the high-speed serial bus, searching a parameter configuration table for a high-speed serial bus parameter that matches all of a frequency of the application signal, a loss of the application signal on the high-speed serial bus, and a material type of a wiring board of the high-speed serial bus, and configuring the high-speed serial bus according to the high-speed serial bus parameter. According to the method, a problem involving configuration of a high-speed serial bus parameter when a transmitted signal is compensated may be solved.