发明申请
US20160137665A1 COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF
有权
包含三亚甲基嘧啶和三烯吡啶化合物的组合物及其使用方法
- 专利标题： COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF
- 专利标题（中）： 包含三亚甲基嘧啶和三烯吡啶化合物的组合物及其使用方法
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申请号： US14937421申请日： 2015-11-10
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公开(公告)号： US20160137665A1公开(公告)日： 2016-05-19
- 发明人: Jolanta Grembecka , Tomasz Cierpicki , Dmitry Borkin , Jay L. Hess , Duxin Sun , Xiaoqin Li
- 申请人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- 主分类号： C07D495/04
- IPC分类号： C07D495/04 ; C07D519/00
摘要：
The present disclosure relates generally to thienopyrimidine and thienopyridine compounds and methods of use thereof. In particular embodiments, the present disclosure provides compositions comprising thienopyrimidine and thienopyridine compounds of Formula 2: and methods of use to inhibit the interaction of menin with MLL1, MLL2 and MLL-fusion oncoproteins.
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