- 专利标题: TREATMENT OF INTRACELLULAR BACTERIAL INFECTION
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申请号: US15011775申请日: 2016-02-01
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公开(公告)号: US20160144053A1公开(公告)日: 2016-05-26
- 发明人: Michael Mattey , James Chadwick
- 申请人: FIXED PHAGE LIMITED
- 优先权: GB1217097.3 20120925
- 主分类号: A61K47/48
- IPC分类号: A61K47/48 ; A01N63/00 ; C12N7/00 ; A61K35/76
摘要:
An intracellular bacterial infection in a plant or animal is treated by administration to a plant cell or animal cell of a particle to which an infectious bacteriophage is covalently attached, wherein the particle is internalised by the cell. Particles with phage attached and compositions comprising the particles are provided. A formulation, for treatment of a bacterial infection, comprises bacteriophage, liquid carrier and adhesive, which dries so that the adhesive adheres the bacteriophage to a surface, one such formulation comprising liquid carrier: 85%-99.98% by weight; bacteriophage: 0.01%-5% by weight; and adhesive: 0.01%-10% by weight.
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