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公开(公告)号：US20160144053A1
公开(公告)日：2016-05-26
申请号：US15011775
申请日：2016-02-01
申请人： FIXED PHAGE LIMITED
发明人： Michael Mattey , James Chadwick
CPC分类号： A61K47/48853 , A01N63/00 , A61K35/76 , A61K47/66 , A61K47/6891 , A61K47/6921 , C12N7/00 , Y02A50/402 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481 , A01N25/04 , A01N25/06 , A01N25/10 , A01N25/24 , A01N2300/00
摘要： An intracellular bacterial infection in a plant or animal is treated by administration to a plant cell or animal cell of a particle to which an infectious bacteriophage is covalently attached, wherein the particle is internalised by the cell. Particles with phage attached and compositions comprising the particles are provided. A formulation, for treatment of a bacterial infection, comprises bacteriophage, liquid carrier and adhesive, which dries so that the adhesive adheres the bacteriophage to a surface, one such formulation comprising liquid carrier: 85%-99.98% by weight; bacteriophage: 0.01%-5% by weight; and adhesive: 0.01%-10% by weight.
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公开(公告)号：US09278141B2
公开(公告)日：2016-03-08
申请号：US14430650
申请日：2013-09-25
申请人： FIXED PHAGE LIMITED
发明人： Michael Mattey , James Chadwick
CPC分类号： A61K47/48853 , A01N63/00 , A61K35/76 , A61K47/48346 , A61K47/48723 , A61K47/66 , A61K47/6891 , A61K47/6921 , C12N7/00 , Y02A50/402 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481 , A01N25/04 , A01N25/06 , A01N25/10 , A01N25/24 , A01N2300/00
摘要： An intracellular bacterial infection in a plant or animal is treated by administration to a plant cell or animal cell of a particle to which an infectious bacteriophage is covalently attached, wherein the particle is internalized by the cell. Particles with phage attached and compositions comprising the particles are provided. A formulation, for treatment of a bacterial infection, comprises bacteriophage, liquid carrier and adhesive, which dries so that the adhesive adheres the bacteriophage to a surface, one such formulation comprising liquid carrier: 85%-99.98% by weight; bacteriophage: 0.01%-5% by weight; and adhesive: 0.01%-10% by weight.
摘要翻译： 植物或动物中的细胞内细菌感染通过施用于感染性噬菌体共价连接的颗粒的植物细胞或动物细胞进行处理，其中所述颗粒被细胞内化。 提供附有噬菌体的颗粒和包含颗粒的组合物。 用于治疗细菌感染的制剂包括噬菌体，液体载体和粘合剂，其干燥，使得粘合剂将噬菌体粘附到表面，一种这样的制剂包含液体载体：85重量％-99.98重量％ 噬菌体：0.01％-5％（重量）; 和粘合剂：0.01重量％-10重量％。
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公开(公告)号：US20150250897A1
公开(公告)日：2015-09-10
申请号：US14430650
申请日：2013-09-25
申请人： FIXED PHAGE LIMITED
发明人： Michael Mattey , James Chadwick
CPC分类号： A61K47/48853 , A01N63/00 , A61K35/76 , A61K47/48346 , A61K47/48723 , A61K47/66 , A61K47/6891 , A61K47/6921 , C12N7/00 , Y02A50/402 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481 , A01N25/04 , A01N25/06 , A01N25/10 , A01N25/24 , A01N2300/00
摘要： An intracellular bacterial infection in a plant or animal is treated by administration to a plant cell or animal cell of a particle to which an infectious bacteriophage is covalently attached, wherein the particle is internalised by the cell. Particles with phage attached and compositions comprising the particles are provided. A formulation, for treatment of a bacterial infection, comprises bacteriophage, liquid carrier and adhesive, which dries so that the adhesive adheres the bacteriophage to a surface, one such formulation comprising liquid carrier: 85%-99.98% by weight; bacteriophage: 0.01%-5% by weight; and adhesive: 0.01%-10% by weight.
摘要翻译： 植物或动物中的细胞内细菌感染通过施用于感染性噬菌体共价连接的颗粒的植物细胞或动物细胞进行处理，其中所述颗粒被细胞内化。 提供附有噬菌体的颗粒和包含颗粒的组合物。 用于治疗细菌感染的制剂包括噬菌体，液体载体和粘合剂，其干燥，使得粘合剂将噬菌体粘附到表面，一种这样的制剂包含液体载体：85重量％-99.98重量％ 噬菌体：0.01％-5％（重量）; 和粘合剂：0.01重量％-10重量％。
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