发明申请
- 专利标题: RNA-CODED ANTIBODY
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申请号: US15053890申请日: 2016-02-25
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公开(公告)号: US20160166690A1公开(公告)日: 2016-06-16
- 发明人: Ingmar HOERR , Jochen PROBST , Steve PASCOLO
- 申请人: CureVac AG
- 申请人地址: DE Tübingen
- 专利权人: CureVac AG
- 当前专利权人: CureVac AG
- 当前专利权人地址: DE Tübingen
- 优先权: DE102007001370.3 20070109
- 主分类号: A61K39/40
- IPC分类号: A61K39/40 ; A61K48/00
摘要:
The present application describes an antibody-coding, non-modified or modified RNA and the use thereof for expression of this antibody, for the preparation of a pharmaceutical composition, in particular a passive vaccine, for treatment of tumours and cancer diseases, cardiovascular diseases, infectious diseases, autoimmune diseases, virus diseases and monogenetic diseases, e.g. also in gene therapy. The present invention furthermore describes an in vitro transcription method, in vitro methods for expression of this antibody using the RNA according to the invention and an in vivo method.
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