An improvement in run-flat, puncture-proof tire structure, in which the foamed inner tire body is formed of foam structure, which can provide the required softness/hardness for the tire by adjusting the proportion of foam material ingredients, and since the foamed inner tire body can be placed in the tire body hollow portion of the outer tire body, therefore it avoids blowout when a sharp object enters into and punctures the outer tire body, and it reduces the risk factors during motion, and the rim section positioned on the wheel rim body holds the inflatable inner tire body, and the inflatable inner tire body is also pressed up against the foamed inner tire body to absorb the vibration formed on the wheel rim body during motion, and since the problems of repair requirement and sudden blowout are still present after a puncture, it provides safety and stability during motion.