Invention Application
US20160206592A1 METHOD FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS BY INHIBITION OF CXCR4/CXCL12 SIGNALING
审中-公开
通过抑制CXCR4 / CXCL12信号治疗多发性前列腺硬化的方法
- Patent Title: METHOD FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS BY INHIBITION OF CXCR4/CXCL12 SIGNALING
- Patent Title (中): 通过抑制CXCR4 / CXCL12信号治疗多发性前列腺硬化的方法
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Application No.: US14915242Application Date: 2014-08-29
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Publication No.: US20160206592A1Publication Date: 2016-07-21
- Inventor: Beka SOLOMON , Inna RABINOVICH-NIKITIN , Beka BARBIRO
- Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
- Applicant Address: IL Tel-Aviv
- Assignee: RAMOT AT TEL-AVIV UNIVERSITY LTD.
- Current Assignee: RAMOT AT TEL-AVIV UNIVERSITY LTD.
- Current Assignee Address: IL Tel-Aviv
- International Application: PCT/US14/53352 WO 20140829
- Main IPC: A61K31/395
- IPC: A61K31/395
Abstract:
The present invention provides use of an inhibitor of G protein-coupled receptor CXCR4 for treating amyotrophic lateral sclerosis (ALS), for inhibiting glutamate release in astrocytes, or for increasing remyelinization in motor neurons.
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