发明申请
US20160213621A1 Melt-Extruded Release Controlled Pharmaceutical Composition and Oral Dosage Form Comprising the Same
审中-公开
熔融挤出释放控制的药物组合物和包含其的口服剂型
- 专利标题： Melt-Extruded Release Controlled Pharmaceutical Composition and Oral Dosage Form Comprising the Same
- 专利标题（中）： 熔融挤出释放控制的药物组合物和包含其的口服剂型
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申请号： US14758258申请日： 2013-12-20
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公开(公告)号： US20160213621A1公开(公告)日： 2016-07-28
- 发明人: Sang-Yeob Park , Hye-Jung Lim , Kyung-Hee Kim
- 申请人： SAMYANG BIOPHARMACEUTICALS CORPORATION
- 优先权： KR10-2012-0158570 20121231
- 国际申请： PCT/KR2013/011972 WO 20131220
- 主分类号： A61K9/50
- IPC分类号： A61K9/50 ; A61K31/519 ; A61K47/32
摘要：
Disclosed are a controlled release pharmaceutical composition, comprising a melt-extruded pellet including a water-insoluble ammonium methacrylate copolymer, a polyvinyl acetate, and an active ingredient; and a polymer coating layer including a water-insoluble ammonium methacrylate copolymer formed on the surface of the pellet, and an oral formulation including the pharmaceutical composition.
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