发明申请
- 专利标题： MTOR-independent activator of TFEB for autophagy enhancement and uses thereof
-
申请号： US15071222申请日： 2016-03-16
-
公开(公告)号： US20160221907A1公开(公告)日： 2016-08-04
- 发明人: Min LI , Juxian SONG , Chuanbin YANG , Yu ZENG , Sandeep MALAMPATI , Hongjie ZHANG
- 申请人： Hong Kong Baptist University
- 主分类号： C07C49/223
- IPC分类号： C07C49/223 ; C07C49/255 ; A61K9/00 ; C07C49/248 ; A61K31/12 ; C07C49/235
摘要：
The present invention relates to a composition comprising an autophagy enhancement compound. Small molecules that are able to enhance autophagy and lysosome biogenesis by activating the gene TFEB which can prevent the accumulation of toxic protein aggregates in treating neurodegenerative diseases are disclosed.
公开/授权文献
信息查询
