Bone Marrow Origin Progenitor Cell or Endothelial Progenitor Cell in Combination with DNMT1 Gene Therapy for Vascular Repair in Metabolic Disease

Invention Application

US20160235789A1 Bone Marrow Origin Progenitor Cell or Endothelial Progenitor Cell in Combination with DNMT1 Gene Therapy for Vascular Repair in Metabolic Disease 有权

Title translation: 骨髓原始祖细胞或内皮祖细胞与DNMT1基因治疗代谢疾病血管修复

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Patent Title: Bone Marrow Origin Progenitor Cell or Endothelial Progenitor Cell in Combination with DNMT1 Gene Therapy for Vascular Repair in Metabolic Disease
Patent Title (中): 骨髓原始祖细胞或内皮祖细胞与DNMT1基因治疗代谢疾病血管修复
Application No.: US15044859

Application Date: 2016-02-16
Publication No.: US20160235789A1

Publication Date: 2016-08-18
Inventor: Hong Wang
Applicant: Temple University-of the Commonwealth System of Higher Education
Main IPC: A61K35/44
IPC: A61K35/44 ; A61K45/06 ; C12N5/071

Bone Marrow Origin Progenitor Cell or Endothelial Progenitor Cell in Combination with DNMT1 Gene Therapy for Vascular Repair in Metabolic Disease

Abstract:

The present invention provides an isolated population of bone marrow-derived endothelial progenitor cells (EPCs) and uses thereof for the treatment of vascular diseases.

Abstract(Chinese):

本发明提供了分离的骨髓来源的内皮祖细胞群（EPCs）及其用于治疗血管疾病的用途。

Public/Granted literature

US09901639B2 Bone marrow origin progenitor cell or endothelial progenitor cell in combination with DNMT1 gene therapy for vascular repair in metabolic disease Public/Granted day:2018-02-27

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Global Dossier Espacenet

IPC分类:

A	人类生活必需
A61	医学或兽医学；卫生学
A61K	医用、牙科用或梳妆用的配制品（专门适用于将药品制成特殊的物理或服用形式的装置或方法A61J3/00；空气除臭，消毒或灭菌，或者绷带、敷料、吸收垫或外科用品的化学方面，或材料的使用入A61L；肥皂组合物入C11D）
A61K35/00	含有其有不明结构的原材料或其反应产物的医用配制品
A61K35/12	.来源于哺乳动物的材料的；包括非特定组织或细胞的组合物；包括非胚胎干细胞的组合物；基因重组细胞（未定性的干细胞；包括抗原或抗体的疫苗或医药配制品入A61K39/00）
A61K35/44	..血管；血管平滑肌细胞；内皮细胞；内皮祖细胞