Methods of performing a fracture operation at a wellsite with a fracture network are provided. The methods involve obtaining wellsite data and a mechanical earth model, and generating a hydraulic fracture growth pattern for the fracture network over time. The generating involves extending hydraulic fractures from a wellbore and into the fracture network of a subterranean formation to form a hydraulic fracture network, determining hydraulic fracture parameters after the extending, determining transport parameters for proppant passing through the hydraulic fracture network, and determining fracture dimensions of the hydraulic fractures from the hydraulic fracture parameters, the transport parameters and the mechanical earth model. The methods also involve performing stress shadowing on the hydraulic fractures to determine stress interference between fractures at different depths, and repeating the generating based on the determined stress interference. The methods may also involve determining crossing behavior.