Invention Application
- Patent Title: CYCLOPROPANAMINE COMPOUND AND USE THEREOF
- Patent Title (中): 环丙基胺化合物及其用途
-
Application No.: US15203551Application Date: 2016-07-06
-
Publication No.: US20160311808A1Publication Date: 2016-10-27
- Inventor: Shigemitsu MATSUMOTO , Yasushi HATTORI , Masashi TOYOFUKU , Shinji MORIMOTO , Masaki DAINI , Takuto KOJIMA , Tomohiro KAKU , Mitsuhiro ITO
- Applicant: Takeda Pharmaceutical Company Limited
- Priority: JP2014-082057 20140411
- Main IPC: C07D409/12
- IPC: C07D409/12 ; C07D231/14 ; C07D285/135 ; C07D407/12 ; C07D413/12 ; C07D333/38 ; C07D277/56 ; C07D417/14 ; C07D413/14 ; C07D417/12 ; C07D213/82

Abstract:
The present invention provides a compound having a lysine-specific demethylase-1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for schizophrenia, developmental disorders, particularly diseases having intellectual disability (e.g., autistic spectrum disorders, Rett syndrome, Down's syndrome, Kabuki syndrome, fragile X syndrome, Kleefstra syndrome, neurofibromatosis type 1, Noonan syndrome, tuberous sclerosis), neurodegenerative diseases (e.g., Alzheimer's disease, Parkinson's disease, spinocerebellar degeneration (e.g., dentatorubural pallidoluysian atrophy) and Huntington's disease), epilepsy (e.g., Dravet syndrome) or drug dependence, and the like. A compound represented by the formula wherein each symbol is as defined in the present specification, or a salt thereof.
Public/Granted literature
- US09714241B2 Cyclopropanamine compound and use thereof Public/Granted day:2017-07-25
Information query