A monitoring device configured for insertion into a conduit of a subject includes a housing, at least one physiological sensor coupled to the housing, a transmitter coupled to the housing, an expandable element, inflatable element, stretched membrane or balloon coupled to the housing and configured to occlude at least a portion of the conduit, a power source attached to the housing, and a processor coupled to the housing and operatively coupled to memory containing computer instruction causing the monitoring device to obtain physiological information via the at least one physiological sensor where the physiological information includes one or more of pulse rate information, body temperature information, breathing rate information, blood pressure information, cardiac output information, or blood gas level information, and processing and analyzing the physiological information to provide a result.