Invention Application
US20160326195A1 TRICYCLIC SULFONES AS RORy MODULATORS 有权
TRICYCLIC SULFONES作为RORY调制器

TRICYCLIC SULFONES AS RORy MODULATORS
Abstract:
There are described RORγ modulators of the formula (I), and formula (II) or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORγ activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORγ activity, for example, autoimmune and/or inflammatory disorders.
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