发明申请
- 专利标题： LENTIVIRAL VECTORS FOR GENERATING IMMUNE RESPONSES AGAINST HUMAN T LYMPHOTROPHIC VIRUS TYPE 1
- 专利标题（中）： 用于产生人类淋巴瘤病毒1型免疫应答的生殖细胞
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申请号： US15112854申请日： 2015-01-27
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公开(公告)号： US20160331831A1公开(公告)日： 2016-11-17
- 发明人: Deborah Revaud , Cecile Bauche
- 申请人： THERAVECTYS
- 优先权： EP14290009.1 20140127
- 国际申请： PCT/IB2015/050598 WO 20150127
- 主分类号： A61K39/21
- IPC分类号： A61K39/21 ; C12N7/00 ; C12N15/86 ; C07K14/005
摘要：
The present invention relates to compositions, methods, and uses employing lentiviral vector particles for induction of an immune response by administration to a human, wherein the lentiviral vector particles comprise a lentiviral vector, wherein the DNA of the lentiviral vector comprises a promoter directing expression of an HTLV-1 Tax and/or HBZ antigen, and/or a p12I and/or p30II antigen. The invention encompasses these vectors, methods of making the vectors, and methods of using them, including medicinal uses.
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