Invention Application
US20160355875A1 METHODS AND KITS FOR DETECTING NUCLEIC ACID SEQUENCES OF INTEREST USING DNA-BINDING PROTEIN DOMAIN
审中-公开
检测利用DNA结合蛋白质域的核酸序列的方法和试剂盒
- Patent Title: METHODS AND KITS FOR DETECTING NUCLEIC ACID SEQUENCES OF INTEREST USING DNA-BINDING PROTEIN DOMAIN
- Patent Title (中): 检测利用DNA结合蛋白质域的核酸序列的方法和试剂盒
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Application No.: US15028644Application Date: 2014-10-10
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Publication No.: US20160355875A1Publication Date: 2016-12-08
- Inventor: Julien VALTON , Alexandre JUILLERAT , Fayza DABOUSSI , Marine BEURDELEY , Claudia BERTONATI , Philippe DUCHATEAU
- Applicant: CELLECTIS
- Priority: DKPA201370578 20131011
- International Application: PCT/EP2014/071812 WO 20141010
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/53
Abstract:
The present invention relates to a method for the detection of a specific nucleic acid. Specifically, the invention provides a method and kits for detecting the presence of a specific nucleic acid using engineered DNA-binding domains such as Transcription Activator Like-Effector (TALE) domain or modular base-per-base binding domains (MBBBD). The method of the invention is particularly useful for in vitro diagnostic application.
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