Invention Application
US20160362448A1 METHODS FOR REDUCING CHROMATIN CONTENT IN PROTEIN PREPARATIONS BY TREATMENT WITH ALKYL CATIONS
审中-公开
通过碱处理降低蛋白质制备中的色素含量的方法
- Patent Title: METHODS FOR REDUCING CHROMATIN CONTENT IN PROTEIN PREPARATIONS BY TREATMENT WITH ALKYL CATIONS
- Patent Title (中): 通过碱处理降低蛋白质制备中的色素含量的方法
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Application No.: US15121686Application Date: 2014-02-27
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Publication No.: US20160362448A1Publication Date: 2016-12-15
- Inventor: Peter Stanley GAGNON
- Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
- International Application: PCT/SG2014/000087 WO 20140227
- Main IPC: C07K1/32
- IPC: C07K1/32 ; C07K1/36 ; C07K16/00
Abstract:
A method of reducing aggregate content in a preparation having a target protein includes contacting the preparation with an alkyl cation to form a mixture, and contacting the mixture with at least one functionalized solid to remove excess alkyl cation.
Public/Granted literature
- US10023609B2 Methods for reducing chromatin content in protein preparations by treatment with alkyl cations Public/Granted day:2018-07-17
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