Invention Application
- Patent Title: SMALL MOLECULE INHIBITORS OF XBP1 SPLICING
- Patent Title (中): XBP1分离小分子抑制剂
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Application No.: US15155258Application Date: 2016-05-16
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Publication No.: US20170007588A1Publication Date: 2017-01-12
- Inventor: Sivanesan Dakshanamurthy , Milton L. Brown , Robert Clarke , Ayesha N. Shajahan-Haq , Jacqueline Smith
- Applicant: GEORGETOWN UNIVERSITY
- Applicant Address: US DC Washington
- Assignee: GEORGETOWN UNIVERSITY
- Current Assignee: GEORGETOWN UNIVERSITY
- Current Assignee Address: US DC Washington
- Main IPC: A61K31/4439
- IPC: A61K31/4439
Abstract:
Small molecule inhibitors of XBP1 splicing by IRE1α are provided, as well as methods for their use in treating or preventing cancer (e.g., endocrine resistant breast cancer), diabetes, and obesity.
Public/Granted literature
- US10806725B2 Small molecule inhibitors of XBP1 splicing Public/Granted day:2020-10-20
Information query
IPC分类:
