Invention Application
US20170009211A1 DOWNREGULATION OF miR-7 FOR PROMOTION OF BETA CELL DIFFERENTIATION AND INSULIN PRODUCTION
审中-公开
用于促进细胞分化和胰岛素生产的miR-7的调控
- Patent Title: DOWNREGULATION OF miR-7 FOR PROMOTION OF BETA CELL DIFFERENTIATION AND INSULIN PRODUCTION
- Patent Title (中): 用于促进细胞分化和胰岛素生产的miR-7的调控
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Application No.: US15278102Application Date: 2016-09-28
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Publication No.: US20170009211A1Publication Date: 2017-01-12
- Inventor: Eran HORNSTEIN , Sharon KREDO-RUSSO
- Applicant: Yeda Research and Development Co. Ltd.
- Applicant Address: IL Rehovot
- Assignee: Yeda Research and Development Co. Ltd.
- Current Assignee: Yeda Research and Development Co. Ltd.
- Current Assignee Address: IL Rehovot
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C07K14/62 ; C12N15/113

Abstract:
A method of ex-vivo increasing insulin content in beta cells or stem cells is disclosed. The method comprising contacting the beta cells or stem cells with an agent for downregulating an activity or expression of miR-7, thereby increasing the insulin content in the beta cells or stem cells.
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