Invention Application
US20170015738A1 Antibodies Specific for Hyperphosphorylated Tau and Methods of Use Thereof
审中-公开
特异于超磷酸化Tau的抗体及其使用方法
- Patent Title: Antibodies Specific for Hyperphosphorylated Tau and Methods of Use Thereof
- Patent Title (中): 特异于超磷酸化Tau的抗体及其使用方法
-
Application No.: US15207836Application Date: 2016-07-12
-
Publication No.: US20170015738A1Publication Date: 2017-01-19
- Inventor: Jan Torleif Pedersen , Lars Østergaard Pedersen , Justus Claus Alfred Daechsel , Ayodeji Abdur-Rasheed Asuni , Nina Helen Rosenqvist
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Valby
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby
- Priority: GB1512211.2 20150713; GB1518375.9 20151016
- Main IPC: C07K16/18
- IPC: C07K16/18 ; G01N33/68 ; A61K49/00
Abstract:
The present invention relates to a novel class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396), as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and tauopathies.
Public/Granted literature
- US10196439B2 Antibodies specific for hyperphosphorylated tau and methods of use thereof Public/Granted day:2019-02-05
Information query
