发明申请
- 专利标题： SOLUBLE HIV-1 ENVELOPE GLYCOPROTEIN TRIMERS
- 专利标题（中）： 可溶性HIV-1环保型糖蛋白TRIMERS
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申请号： US14508369申请日： 2014-10-07
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公开(公告)号： US20170035877A1公开(公告)日： 2017-02-09
- 发明人: Richard Wyatt , Andrew Ward , Karen Tran , Shailendra Kumar , Jidnyasa Ingale , Javier Guenaga , Yu Feng , Viktoria Dubrowskaya , Natalia de Val Alta
- 申请人： International AIDS Vaccine Initiative , The Scripps Research Institute
- 主分类号： A61K39/21
- IPC分类号： A61K39/21 ; C07K14/005 ; C12N7/00
摘要：
The present application relates to novel HIV-1 envelope glycoproteins which may be utilized as an HIV-1 vaccine immunogens, antigens for crystallization and for the identification of broad neutralizing antibodies. The present invention encompasses the preparation and purification of immunogenic compositions which are formulated into the vaccines of the present invention.
公开/授权文献
- US10058604B2 Soluble HIV-1 envelope glycoprotein trimers 公开/授权日：2018-08-28
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