Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38

Invention Application

US20170044265A1 Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38 审中-公开

Title translation: 用具体绑定CD38的抗体对实体肿瘤的免疫调节和治疗

Patent Title: Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38
Patent Title (中): 用具体绑定CD38的抗体对实体肿瘤的免疫调节和治疗
Application No.: US15340214

Application Date: 2016-11-01
Publication No.: US20170044265A1

Publication Date: 2017-02-16
Inventor: Tahamtan Ahmadi , Tineke Casneuf , Henk Lokhorst , Tuna Mutis , Amy Sasser , Niels van de Donk
Applicant: Janssen Biotech, Inc.
Main IPC: C07K16/28
IPC: C07K16/28 ; A61K38/47 ; A61K39/395 ; C07K16/40 ; C07K16/30

Abstract:

The present invention relates to methods of immunomodulation and treating patients having solid tumors with antibodies that specifically bind CD38.

Abstract(Chinese):

本发明涉及用具有特异性结合CD38的抗体免疫调节和治疗具有实体瘤患者的方法。

Information query

Global Dossier Espacenet

IPC分类:

C	化学；冶金
C07	有机化学
C07K	肽（含有β-内酰胺的肽入C07D；在分子中除了形成本身的肽环外不含有任何其他的肽键的环状二肽，如哌嗪-2,5-二酮入C07D；环肽型麦角生物碱入C07D519/02；单细胞蛋白质、酶入C12N；获得肽的基因工程方法入C12N15/00）
C07K16/00	免疫球蛋白，例如，单克隆或多克隆抗体
C07K16/18	.抗来自动物或人的物质
C07K16/28	..抗受体，细胞表面抗原或细胞表面决定因子