公开(公告)号：US11618787B2

公开(公告)日：2023-04-04

申请号：US16177239

申请日：2018-10-31

Applicant: Janssen Biotech, Inc.

Inventor： Tahamtan Ahmadi ,  Christopher Chiu ,  Ming Qi ,  Amy Sasser ,  Jordan Schecter

IPC: C07K16/28 ,  A61K39/395 ,  A61P35/00 ,  A61K31/573 ,  A61K31/495 ,  A61K31/4439 ,  A61K31/69 ,  A61K9/00 ,  A61K31/454 ,  A61K39/00

Abstract: Disclosed are methods of treating a subject having high-risk multiple myeloma, methods of achieving negative minimal residual disease status in a subject having multiple myeloma, and methods of predicting a likelihood of, or decreasing a risk of, relapse and/or disease progression in a subject having multiple myeloma.

公开(公告)号：US20210403592A1

公开(公告)日：2021-12-30

申请号：US17329057

申请日：2021-05-24

Applicant: Janssen Biotech, Inc.

Inventor： Tahamtan Ahmadi ,  Tineke Casneuf ,  Henk Lokhorst ,  Tuna Mutis ,  Amy Sasser ,  Niels van de Donk

IPC: C07K16/28 ,  C07K16/40 ,  A61K39/395 ,  A61K38/47 ,  A61K45/06 ,  A61K31/454 ,  A61K31/573

Abstract: The present invention relates to methods of immunomodulation and treating patients having solid tumors with antibodies that specifically bind CD38.

公开(公告)号：US20250066501A1

公开(公告)日：2025-02-27

申请号：US18825958

申请日：2024-09-05

Applicant: Janssen Biotech, Inc.

Inventor： Tahamtan Ahmadi ,  Tineke Casneuf ,  Henk Lokhorst ,  Tuna Mutis ,  Amy Sasser ,  Niels van de Donk

IPC: C07K16/28 ,  A61K31/454 ,  A61K31/573 ,  A61K38/47 ,  A61K39/00 ,  A61K39/395 ,  A61K45/06 ,  C07K16/40

Abstract: The present invention relates to methods of immunomodulation and treating patients having solid tumors with antibodies that specifically bind CD38.

公开(公告)号：US20190144557A1

公开(公告)日：2019-05-16

申请号：US16162355

申请日：2018-10-16

Applicant: Janssen Biotech, Inc.

Inventor： Tahamtan Ahmadi ,  Tineke Casneuf ,  Henk Lokhorst ,  Tuna Mutis ,  Amy Sasser ,  Niels van de Donk

IPC: C07K16/28 ,  A61K39/395 ,  A61K45/06 ,  A61K31/454 ,  A61K31/573 ,  A61K38/47 ,  C07K16/40

Abstract: The present invention relates to methods of immunomodulation and treating patients having solid tumors with antibodies that specifically bind CD38.

公开(公告)号：US20190127479A1

公开(公告)日：2019-05-02

申请号：US16177239

申请日：2018-10-31

Applicant: Janssen Biotech, Inc.

Inventor： Tahamtan Ahmadi ,  Christopher Chiu ,  Ming Qi ,  Amy Sasser ,  Jordan Schecter

IPC: C07K16/28 ,  A61P35/00 ,  A61K31/573 ,  A61K31/4439 ,  A61K31/69 ,  A61K9/00 ,  A61K39/395

Abstract: Disclosed are methods of treating a subject having high-risk multiple myeloma, methods of achieving negative minimal residual disease status in a subject having multiple myeloma, and methods of predicting a likelihood of, or decreasing a risk of, relapse and/or disease progression in a subject having multiple myeloma.

公开(公告)号：US20230340145A1

公开(公告)日：2023-10-26

申请号：US18175345

申请日：2023-02-27

Applicant: Janssen Biotech, Inc.

Inventor： Tahamtan Ahmadi ,  Christopher Chiu ,  Ming Qi ,  Amy Sasser ,  Jordan Schecter

IPC: C07K16/28 ,  A61P35/00 ,  A61K31/573 ,  A61K31/4439 ,  A61K31/69 ,  A61K39/395 ,  A61K9/00 ,  A61K31/454

CPC classification number: C07K16/2896 ,  A61P35/00 ,  A61K31/573 ,  A61K31/4439 ,  A61K31/69 ,  A61K39/3955 ,  A61K9/0019 ,  A61K31/454 ,  C07K2317/34 ,  C07K2317/565 ,  A61K2039/54

Abstract: Disclosed are methods of treating a subject having high-risk multiple myeloma, methods of achieving negative minimal residual disease status in a subject having multiple myeloma, and methods of predicting a likelihood of, or decreasing a risk of, relapse and/or disease progression in a subject having multiple myeloma.

公开(公告)号：US11021543B2

公开(公告)日：2021-06-01

申请号：US16162355

申请日：2018-10-16

Applicant: Janssen Biotech, Inc.

Inventor： Tahamtan Ahmadi ,  Tineke Casneuf ,  Henk Lokhorst ,  Tuna Mutis ,  Amy Sasser ,  Niels van de Donk

IPC: C07K16/28 ,  A61K39/395 ,  C07K16/40 ,  A61K38/47 ,  A61K45/06 ,  A61K31/454 ,  A61K31/573 ,  A61K39/00

Abstract: The present invention relates to methods of immunomodulation and treating patients having solid tumors with antibodies that specifically bind CD38.

公开(公告)号：US20170044265A1

公开(公告)日：2017-02-16

申请号：US15340214

申请日：2016-11-01

Applicant: Janssen Biotech, Inc.

Inventor： Tahamtan Ahmadi ,  Tineke Casneuf ,  Henk Lokhorst ,  Tuna Mutis ,  Amy Sasser ,  Niels van de Donk

IPC: C07K16/28 ,  A61K38/47 ,  A61K39/395 ,  C07K16/40 ,  C07K16/30

CPC classification number: C07K16/2896 ,  A61K31/454 ,  A61K31/573 ,  A61K38/47 ,  A61K39/39558 ,  A61K45/06 ,  A61K2039/505 ,  A61K2039/545 ,  A61K2039/55 ,  C07K16/40 ,  C07K2317/56 ,  C07K2317/565 ,  C12Y204/99 ,  C12Y302/01035 ,  A61K2300/00

Abstract: The present invention relates to methods of immunomodulation and treating patients having solid tumors with antibodies that specifically bind CD38.

Abstract translation: 本发明涉及用具有特异性结合CD38的抗体免疫调节和治疗具有实体瘤患者的方法。

公开(公告)号：US20160376373A1

公开(公告)日：2016-12-29

申请号：US15191808

申请日：2016-06-24

Applicant: Janssen Biotech, Inc.

Inventor： Tahamtan Ahmadi ,  Tineke Casneuf ,  Henk Lokhorst ,  Tuna Mutis ,  Amy Sasser

IPC: C07K16/28 ,  A61K45/06 ,  C07K16/40 ,  A61K39/395

CPC classification number: C07K16/2896 ,  A61K39/39558 ,  A61K45/06 ,  A61K2039/505 ,  A61K2039/507 ,  A61K2039/545 ,  A61P35/00 ,  A61P37/04 ,  C07K16/2803 ,  C07K16/2818 ,  C07K16/2827 ,  C07K16/40 ,  C07K2317/31 ,  C07K2317/34 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/70 ,  C07K2317/732 ,  C07K2317/76

Abstract: The present invention relates to methods of immunomodulation and treating patients having solid tumors with antibodies that specifically bind CD38.

Abstract translation: 本发明涉及用具有特异性结合CD38的抗体免疫调节和治疗具有实体瘤患者的方法。