Invention Application
- Patent Title: PROCESS FOR THE PREPARATION OF (E)-3-(4-((E)-2-(2-CHLORO-4-FLUOROPHENYL)-1-(1H-INDAZOL-5-YL)BUT-1-EN-1-YL)PHENYL)ACRYLIC ACID
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Application No.: US15287023Application Date: 2016-10-06
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Publication No.: US20170101380A1Publication Date: 2017-04-13
- Inventor: Stephan Bachmann , Serena Maria Fantasia , Francis Gosselin , Chong Han , Stefan Hildbrand , Theresa Humphries , Christian Jenny , Ngiap-Kie Lim , Andrew McClory , Christian Moessner , Pankaj Rege , Scott Savage , Haiming Zhang
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Main IPC: C07D231/56
- IPC: C07D231/56 ; C07C309/73 ; C07C69/73 ; C07F5/04 ; C07D405/04
Abstract:
Processes are described for the preparation of estrogen receptor modulating compound, (E)-3-(4-((E)-2-(2-chloro-4-fluorophenyl)-1-(1H-indazol-5-yl)but-1-en-1-yl)phenyl)acrylic acid I: and salts thereof, and intermediates useful for the preparation of I.
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