Invention Application
- Patent Title: 2'-Ethynyl Nucleoside Derivatives for Treatment of Viral Infections
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Application No.: US15378576Application Date: 2016-12-14
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Publication No.: US20170112868A1Publication Date: 2017-04-27
- Inventor: Sampath-Kumar Anandan , Virender Singh Aulakh , Martijn Fenaux , Xiaodong Lin , Liang Mao , Oliver Saunders , Zachary Kevin Sweeney , Fumiaki Yokokawa , Weidong Zhong
- Applicant: Novartis AG
- Priority: CNPCT/CN2013/073443 20130329
- Main IPC: A61K31/7072
- IPC: A61K31/7072 ; A61K45/06 ; A61K47/22 ; C07H19/06
Abstract:
The present invention provides a compound of formula A: or a pharmaceutically acceptable salt thereof, wherein B, Q, R1, R5, R6, R7, R8 and Z are defined herein, which is a 2′-branched nucleoside useful for the treatment or prevention of viral infections, particularly dengue virus, yellow fever virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, Kunjin virus, Murray Valley encephalitis, St Louis encephalitis, Omsk hemorrhagic fever virus, bovine viral diarrhea virus, Zika virus and Hepatitis C virus.
Public/Granted literature
- US09814739B2 2′-ethynyl nucleoside derivatives for treatment of viral infections Public/Granted day:2017-11-14
Information query
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