A method and apparatus are disclosed for switching communication interface in a wireless communication system. In one embodiment, the method includes a UE using a first interface to transmit data for a service. The method also includes the UE receiving an information from a base station for indicating that the first interface is not allowed to transmit data for the service. The method further includes the UE transmitting a request to the base station for using a second interface in response to the reception of the information.