Invention Application
- Patent Title: HEPATITIS B ANTIVIRAL AGENTS
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Application No.: US15450125Application Date: 2017-03-06
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Publication No.: US20170253609A1Publication Date: 2017-09-07
- Inventor: Yao-Ling Qiu , Xuri Gao , Wei Li , Hui Cao , Meizhong Jin , Jorden Kass , Xiaowen Peng , Yat Sun Or
- Applicant: ENANTA PHARMACEUTICALS, INC.
- Main IPC: C07D493/08
- IPC: C07D493/08 ; A61K31/357 ; C07C317/32 ; A61K31/167 ; A61K31/223 ; C07C323/42 ; C07C235/56 ; C07D313/04 ; A61K31/335 ; C07D213/52 ; A61K31/4402 ; C07D213/89 ; A61K31/4425 ; A61K31/4409 ; C07D213/81 ; A61K31/44 ; C07C311/53 ; A61K31/18 ; C07D211/54 ; A61K31/445 ; C07D309/08 ; A61K31/351 ; C07D303/34 ; A61K31/336 ; C07D493/04 ; C07D401/04 ; A61K31/4545 ; C07D307/33 ; A61K31/365 ; C07D307/32 ; A61K31/341 ; A61K31/196 ; A61K31/325 ; A61K31/655 ; A61K31/215 ; C07B59/00 ; C07D261/20 ; A61K31/416 ; C07D261/02 ; A61K31/415 ; C07D261/08 ; C07D451/04 ; A61K31/439 ; C07D231/12 ; C07D263/52 ; A61K31/421 ; C07D327/10 ; A61K31/39 ; C07D207/16 ; A61K31/401 ; C07D257/04 ; A61K31/41 ; C07D233/64 ; A61K31/4164 ; A61K31/277 ; C07D277/26 ; A61K31/426 ; C07D295/088 ; A61K31/5377 ; C07D303/26 ; C07D317/72
Abstract:
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: X-A-Y-L-R (I) which inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV life cycle of the hepatitis B virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV infection. The invention also relates to methods of treating an HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
Public/Granted literature
- US10179792B2 Hepatitis B antiviral agents Public/Granted day:2019-01-15
Information query
