- 专利标题： MODULATORS OF THE EIF2ALPHA PATHWAY
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申请号： US15614278申请日： 2017-06-05
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公开(公告)号： US20170342020A1公开(公告)日： 2017-11-30
- 发明人: Peter Walter , Carmela Sidrauski , Diego Acosta Alvear , Michelle R. Arkin , Christopher G. Wilson , Kean Hooi Ang , Brian R. Hearn , Punitha Vedantham , Adam R. Renslo , Mervyn Maze , Susana Vacas
- 申请人： The Regents of the University of California
- 主分类号： C07C235/14
- IPC分类号： C07C235/14 ; C07D495/04 ; A61K31/165 ; C07D403/12 ; C07C323/60 ; C07C317/44 ; C07C317/22 ; C07C271/52 ; C07C271/24 ; C07C257/14 ; C07C255/54 ; C07C235/24 ; C07C235/22 ; C07C235/20 ; C07C211/29 ; A61K31/4192 ; C07F7/08 ; C07C2601/14 ; C07C2601/04
摘要：
Provided herein, inter alia, are compounds and methods useful for modulating the translational effects of eIF2α phosphorylation, the Integrated Stress Response (ISR), and the unfolded protein response (UPR); for treating diseases; for increasing protein production, and for improving long-term memory.
公开/授权文献
- US10343981B2 Modulators of the eIF2alpha pathway 公开/授权日：2019-07-09
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