- 专利标题: DRUG RELEASING COATINGS FOR MEDICAL DEVICES
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申请号: US15654226申请日: 2017-07-19
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公开(公告)号: US20180036458A1公开(公告)日: 2018-02-08
- 发明人: Lixiao Wang
- 申请人: Lutonix, Inc.
- 主分类号: A61L31/16
- IPC分类号: A61L31/16 ; A61K31/436 ; A61L29/08 ; A61K31/337 ; A61L31/08 ; A61L29/16
摘要:
Medical device are provided for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. In certain embodiments, the additive has a hydrophilic part and a drug affinity part, wherein the drug affinity part is at least one of a hydrophobic part, a part that has an affinity to the therapeutic agent by hydrogen bonding, and a part that has an affinity to the therapeutic agent by van der Waals interactions. In embodiments, the additive is water-soluble. In further embodiments, the additive is at least one of a surfactant and a chemical compound, and the chemical compound has a molecular weight of from 80 to 750 or has more than four hydroxyl groups.
公开/授权文献
- US10994055B2 Drug releasing coatings for medical devices 公开/授权日:2021-05-04