Invention Application
- Patent Title: PHOSPHATE SUBSTITUTED QUINOLIZINE DERIVATIVES USEFUL AS HIV INTEGRASE INHIBITORS
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Application No.: US15560896Application Date: 2016-03-25
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Publication No.: US20180051043A1Publication Date: 2018-02-22
- Inventor: Tao Yu , Sherman T. Waddell , John A. McCauley , Thomas H. Graham , Hong Li , Izzat Raheem , Jay A. Grobler
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- International Application: PCT/US16/24193 WO 20160325
- Main IPC: C07F9/6561
- IPC: C07F9/6561 ; A61K31/683 ; A61K31/675
Abstract:
The present invention relates to Phosphate Substituted Quinolizine Derivatives of Formula (I): and pharmaceutically acceptable salts or prodrug thereof, wherein X, Y, R1, R2, R3, R4, R5, R9 and R10 are as defined herein. The present invention also relates to compositions comprising at least one Phosphate Substituted Quinolizine Derivative, and methods of using the Phosphate Substituted Quinolizine Derivatives for treating or preventing HIV infection in a subject.
Public/Granted literature
- US10081647B2 Phosphate substituted quinolizine derivatives useful as HIV integrase inhibitors Public/Granted day:2018-09-25
Information query
