GUIDE RNA WITH CHEMICAL MODIFICATIONS

Invention Application

US20180051281A1 GUIDE RNA WITH CHEMICAL MODIFICATIONS 审中-公开

Please log in to see more content

Patent Title: GUIDE RNA WITH CHEMICAL MODIFICATIONS
Application No.: US15607295

Application Date: 2017-05-26
Publication No.: US20180051281A1

Publication Date: 2018-02-22
Inventor: Daniel E. Ryan , Douglas J. Dellinger , Jeffrey R. Sampson , Robert Kaiser , Joel Myerson
Applicant: Agilent Technologies, Inc.
Main IPC: C12N15/11
IPC: C12N15/11 ; C12N9/22 ; C12N15/113 ; C12N2310/20

Abstract:

The present invention relates to modified guide RNAs and their use in clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems.

Public/Granted literature

US10337001B2 Guide RNA with chemical modifications Public/Granted day:2019-07-02

Information query

Global Dossier Espacenet

IPC分类:

C	化学；冶金
C12	生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程
C12N	微生物或酶；其组合物；繁殖、保藏或维持微生物；变异或遗传工程；培养基（微生物学的试验介质入C12Q1/00）。
C12N15/00	突变或遗传工程；遗传工程涉及的DNA或RNA，载体（如质粒）或其分离、制备或纯化；所使用的宿主（突变体或遗传工程制备的微生物本身入C12N1/00、C12N5/00、C12N7/00；新的植物入A01H；用组织培养技术再生植物入A01H4/00；新的动物入A01K67/00；含有插入活体细胞的遗传物质以治疗遗传疾病的药剂的应用，基因疗法入A61K48/00，一般肽入C07K）
C12N15/09	.DNA重组技术
C12N15/11	..DNA或RNA片段；其修饰形成（不用于重组技术的DNA或RNA入C07H21/00）