A medical manipulator having: a first rotatable body configured to be rotated about a rotation axis to exert a driving force transmitted by a wire to drive at least one of an elongated portion and an end effector; and a second rotatable body configured to be detachably coupled to the first rotatable body, wherein the second rotatable body is operatively connected to an actuator to be rotated by the actuator, wherein a shape of the first rotatable body corresponds to a shape of the second rotatable body such that as the first rotatable body and the second rotatable body are brought into contact with each other, a pressing force with which the first rotatable body is pressed against the second rotatable body is converted into a rotational force of the second rotatable body to rotate the second rotatable body into a predetermined alignment with the first rotatable body.