Invention Application
- Patent Title: PYRIDINYL QUINOLINONE DERIVATIVES AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS
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Application No.: US15677748Application Date: 2017-08-15
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Publication No.: US20180086733A1Publication Date: 2018-03-29
- Inventor: Jian Lin , Anna Ericsson , Ann-Marie Campbell , Gary Gustafson , Zhongguo Wang , R. Bruce Diebold , Susan Ashwell , David R. Lancia, JR. , Justin Andrew Caravella , Wei Lu
- Applicant: FORMA Therapeutics, Inc.
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D417/14 ; C07D413/14 ; C07D405/14 ; C07D401/14 ; A61K31/4704
Abstract:
The invention relates to inhibitors of mutant isocitrate dehydrogenase (mt-IDH) proteins with neomorphic activity useful in the treatment of cell-proliferation disorders and cancers, having the Formula: where A, B, U, V, Z, W1, W2, W3, and R1-R6 are described herein.
Information query
