- 专利标题: CYCLOPROPANAMINE COMPOUND AND USE THEREOF
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申请号: US15882386申请日: 2018-01-29
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公开(公告)号: US20180162853A1公开(公告)日: 2018-06-14
- 发明人: Shigemitsu MATSUMOTO , Yasushi HATTORI , Masashi TOYOFUKU , Shinji MORIMOTO , Masaki DAINI , Takuto KOJIMA , Tomohiro KAKU , Mitsuhiro ITO
- 申请人: Takeda Pharmaceutical Company Limited
- 优先权: JP2014-082057 20140411
- 主分类号: C07D417/14
- IPC分类号: C07D417/14 ; C07D333/38 ; C07D413/14 ; C07D407/12 ; C07D307/79 ; C07D409/12 ; C07D417/12 ; C07D307/81 ; C07D413/12 ; C07D409/14 ; C07D231/12 ; C07D277/56 ; C07D285/135 ; C07D285/08 ; C07D333/40 ; C07D231/14 ; C07D213/82
摘要:
The present invention provides a compound having a lysine-specific demethylase-1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for schizophrenia, developmental disorders, particularly diseases having intellectual disability (e.g., autistic spectrum disorders, Rett syndrome, Down's syndrome, Kabuki syndrome, fragile X syndrome, Kleefstra syndrome, neurofibromatosis type 1, Noonan syndrome, tuberous sclerosis), neurodegenerative diseases (e.g., Alzheimer's disease, Parkinson's disease, spinocerebellar degeneration (e.g., dentatorubural pallidoluysian atrophy) and Huntington's disease), epilepsy (e.g., Dravet syndrome) or drug dependence, and the like. A compound represented by the formula wherein each symbol is as defined in the present specification, or a salt thereof.
公开/授权文献
- US10414761B2 Cyclopropanamine compound and use thereof 公开/授权日:2019-09-17
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